Pseudomonas aeruginosa PAO1, PA5082 (dguC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5082
Name
dguC
Replicon chromosome
Genomic location 5720950 - 5721849 (- strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253769.1
GI 15600275
Affymetrix PA5082_at
Entrez 880087
GenBank AAG08467.1
INSDC AAG08467.1
NCBI Locus Tag PA5082
protein_id(GenBank) gb|AAG08467.1|AE004921_4|gnl|PseudoCAP|PA5082
TIGR NTL03PA05083
UniParc UPI00000C5EF0
UniProtKB Acc Q9HUA1
UniProtKB ID Q9HUA1_PSEAE
UniRef100 UniRef100_Z2DK35
UniRef50 UniRef50_Q1LRE1
UniRef90 UniRef90_V6AN01

Product

Feature Type CDS
Coding Frame 1
Product Name
DguC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.90
Kyte-Doolittle Hydrophobicity Value -0.297
Molecular Weight (kDa) 32.9
Isoelectric Point (pI) 8.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 412 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004683 (399 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5082
Search term: dguC
Search term: DguC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Functional characterization of the dguRABC locus for D-Glu and d-Gln utilization in Pseudomonas aeruginosa PAO1.
He W, Li G, Yang CK, Lu CD
Microbiology (Reading) 2014 Oct;160(Pt 10):2331-2340
PubMed ID: 25082951