Pseudomonas aeruginosa PAO1, PA5088 (tli5b3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5088
Name
tli5b3
Replicon chromosome
Genomic location 5726357 - 5727238 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253775.1
GI 15600281
Affymetrix PA5088_at
Entrez 882244
GenBank AAG08473.1
INSDC AAG08473.1
NCBI Locus Tag PA5088
protein_id(GenBank) gb|AAG08473.1|AE004921_10|gnl|PseudoCAP|PA5088
TIGR NTL03PA05089
UniParc UPI00000C5EF5
UniProtKB Acc Q9HU95
UniProtKB ID Q9HU95_PSEAE
UniRef100 UniRef100_Q9HU95
UniRef50 UniRef50_Q9HU95
UniRef90 UniRef90_Q9HU95

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion lipase immunity protein, Tli5b3
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.42
Kyte-Doolittle Hydrophobicity Value -0.352
Molecular Weight (kDa) 32.9
Isoelectric Point (pI) 5.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5JJO IMMUNE SYSTEM 04/24/16 The crystal structure of immunity protein PA5088 from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA PAO1 2.002 X-RAY DIFFRACTION 99.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 79 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004686 (201 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5088
Search term: tli5b3

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
PubMed ID: 27376031