Pseudomonas aeruginosa PAO1, PA5092 (hutI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5092
Name
hutI
Replicon chromosome
Genomic location 5732909 - 5734117 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253779.1
GI 15600285
Affymetrix PA5092_hutI_at
Entrez 878339
GenBank AAG08477.1
INSDC AAG08477.1
NCBI Locus Tag PA5092
protein_id(GenBank) gb|AAG08477.1|AE004922_2|gnl|PseudoCAP|PA5092
TIGR NTL03PA05093
UniParc UPI000012CEA9
UniProtKB Acc Q9HU91
UniProtKB ID HUTI_PSEAE
UniRef100 UniRef100_Q9HU91
UniRef50 UniRef50_Q8U8Z6
UniRef90 UniRef90_Q9HU91

Product

Feature Type CDS
Coding Frame 1
Product Name
imidazolone-5-propionate hydrolase HutI
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.56
Kyte-Doolittle Hydrophobicity Value -0.008
Molecular Weight (kDa) 43.4
Isoelectric Point (pI) 5.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 286 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004689 (521 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5092
Search term: hutI

Human Homologs

Ensembl 94, assembly GRCh38.p12
amidohydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28577]
E-value: 2.6e-60
Percent Identity: 37.4

References

Cloning and sequencing of a 29 kb region of the Bacillus subtilis genome containing the hut and wapA loci.
Yoshida K, Sano H, Seki S, Oda M, Fujimura M, Fujita Y
Microbiology (Reading, Engl.) 1995 Feb;141 ( Pt 2)
PubMed ID: 7704263