Pseudomonas aeruginosa PAO1, PA5093

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5093
Name
Replicon chromosome
Genomic location 5734114 - 5735646 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253780.1
GI 15600286
Affymetrix PA5093_at
Entrez 878340
GenBank AAG08478.1
INSDC AAG08478.1
NCBI Locus Tag PA5093
protein_id(GenBank) gb|AAG08478.1|AE004922_3|gnl|PseudoCAP|PA5093
TIGR NTL03PA05094
UniParc UPI00000C5EF9
UniProtKB Acc Q9HU90
UniProtKB ID Q9HU90_PSEAE
UniRef100 UniRef100_W0Z1I3
UniRef50 UniRef50_I2BL16
UniRef90 UniRef90_A6VDL1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable histidine/phenylalanine ammonia-lyase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -4.82
Kyte-Doolittle Hydrophobicity Value 0.235
Molecular Weight (kDa) 53.5
Isoelectric Point (pI) 6.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 301 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004690 (442 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5093

Human Homologs

Ensembl 110, assembly GRCh38.p14
histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]
E-value: 9.5e-83
Percent Identity: 37.9

References

Histidine ammonia-lyase from Streptomyces griseus.
Wu PC, Kroening TA, White PJ, Kendrick KE
Gene 1992 Jun 15;115(1-2):19-25
PubMed ID: 1612436