Pseudomonas aeruginosa PAO1, PA5094

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5094
Name
Replicon chromosome
Genomic location 5735643 - 5736473 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253781.1
GI 15600287
Affymetrix PA5094_at
DNASU PaCD00008190
Entrez 878341
GenBank AAG08479.1
INSDC AAG08479.1
NCBI Locus Tag PA5094
protein_id(GenBank) gb|AAG08479.1|AE004922_4|gnl|PseudoCAP|PA5094
TIGR NTL03PA05095
UniParc UPI00000C5EFA
UniProtKB Acc Q9HU89
UniProtKB ID Q9HU89_PSEAE
UniRef100 UniRef100_Q9HU89
UniRef50 UniRef50_D7I684
UniRef90 UniRef90_Q9HU89

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.86
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 30.7
Isoelectric Point (pI) 9.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004691 (971 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5094

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33]
E-value: 2.1e-23
Percent Identity: 33.5
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33]
E-value: 2.1e-23
Percent Identity: 33.5

References

Molecular characterization of the proU loci of Salmonella typhimurium and Escherichia coli encoding osmoregulated glycine betaine transport systems.
Stirling DA, Hulton CS, Waddell L, Park SF, Stewart GS, Booth IR, Higgins CF
Mol Microbiol 1989 Aug;3(8):1025-38
PubMed ID: 2691838