Pseudomonas aeruginosa UCBPP-PA14, PA14_03220 (vgrG2b)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_03220
Name
vgrG2b
Replicon chromosome
Genomic location 285213 - 288272 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 48 transposon mutants in orthologs

Cross-References

RefSeq YP_788415.1
GI 116053975
Entrez 4383673
INSDC ABJ15211.1
NCBI Locus Tag PA14_03220
UniParc UPI000045D3C1
UniProtKB Acc Q02UH1
UniProtKB ID Q02UH1_PSEAB
UniRef100 UniRef100_Q02UH1
UniRef50 UniRef50_Q9I3K1
UniRef90 UniRef90_Q9I3K1

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG2b
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -24.57
Kyte-Doolittle Hydrophobicity Value -0.487
Molecular Weight (kDa) 113.1
Isoelectric Point (pI) 5.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 146 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_03220
Search term: vgrG2b
Search term: VgrG2b

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999
Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network.
Sana TG, Baumann C, Merdes A, Soscia C, Rattei T, Hachani A, Jones C, Bennett KL, Filloux A, Superti-Furga G, Voulhoux R, Bleves S.
MBio. 2015 Jun 2;6(3):e00712.
PubMed ID: 26037124