Pseudomonas aeruginosa UCBPP-PA14, PA14_19020 (tse3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_19020
Name
tse3
Replicon chromosome
Genomic location 1642132 - 1643358 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_789663.1
GI 116051502
Entrez 4381468
INSDC ABJ12738.1
NCBI Locus Tag PA14_19020
UniParc UPI00003960CA
UniProtKB Acc Q02QX3
UniProtKB ID Q02QX3_PSEAB
UniRef100 UniRef100_Q02QX3
UniRef50 UniRef50_Q9HYC5
UniRef90 UniRef90_Q9HYC5

Product

Feature Type CDS
Coding Frame 1
Product Name
Tse3
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 2.97
Kyte-Doolittle Hydrophobicity Value -0.197
Molecular Weight (kDa) 44.4
Isoelectric Point (pI) 9.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4LUQ PROTEIN BINDING/TOXIN INHIBITOR 07/25/13 Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3 PSEUDOMONAS AERUGINOSA 1.77 X-RAY DIFFRACTION 99.8
4N80 HYDROLASE/HYDROLASE INHIBITOR 10/16/13 Crystal structure of Tse3-Tsi3 complex PSEUDOMONAS AERUGINOSA 2.4 X-RAY DIFFRACTION 99.7
4M5E HYDROLASE 08/08/13 Tse3 structure PSEUDOMONAS AERUGINOSA 1.49 X-RAY DIFFRACTION 99.8
4N88 HYDROLASE/HYDROLASE INHIBITOR 10/17/13 Crystal structure of Tse3-Tsi3 complex with calcium ion PSEUDOMONAS AERUGINOSA 2.8 X-RAY DIFFRACTION 99.8
4N7S HYDROLASE/HYDROLASE INHIBITOR 10/16/13 Crystal structure of Tse3-Tsi3 complex with Zinc ion PSEUDOMONAS AERUGINOSA 2.101 X-RAY DIFFRACTION 99.8
4M5F HYDROLASE INHIBITOR 08/08/13 complex structure of Tse3-Tsi3 PSEUDOMONAS AERUGINOSA 2.5 X-RAY DIFFRACTION 99.8
3WA5 HYDROLASE 04/26/13 Crystal Structure of type VI peptidoglycan muramidase effector Tse3 in complex with its cognate immunity protein Tsi3 PSEUDOMONAS AERUGINOSA 1.9 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002158 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_19020
Search term: tse3
Search term: Tse3

References

PubMed ID: 28673999
PubMed ID: 23695568
PubMed ID: 24025333
PubMed ID: 24724564
PubMed ID: 24100309