Pseudomonas aeruginosa UCBPP-PA14, PA14_21480 (tli1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_21480
Name
tli1
Replicon chromosome
Genomic location 1862506 - 1863060 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_789862.1
GI 116051306
Entrez 4381310
INSDC ABJ12542.1
NCBI Locus Tag PA14_21480
UniParc UPI0000E44994
UniProtKB Acc Q02QC4
UniProtKB ID Q02QC4_PSEAB
UniRef100 UniRef100_Q02QC4
UniRef50 UniRef50_Q9HYV2
UniRef90 UniRef90_Q9HYV2

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion lipase immunity protein, Tli1
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 5.94
Kyte-Doolittle Hydrophobicity Value -0.292
Molecular Weight (kDa) 20.4
Isoelectric Point (pI) 8.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002323 (150 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_21480
Search term: tli1

Human Homologs

References

Type VI secretion system effectors: poisons with a purpose.
Russell AB, Peterson SB, Mougous JD
Nat Rev Microbiol 2014 Feb;12(2):137-48
PubMed ID: 24384601