Pseudomonas aeruginosa UCBPP-PA14, PA14_33990 (clpV3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_33990
Name
clpV3
Replicon chromosome
Genomic location 3021340 - 3023889 (- strand)
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_790872.1
GI 116050311
Entrez 4380432
INSDC ABJ11547.1
NCBI Locus Tag PA14_33990
UniParc UPI0000396AC2
UniProtKB Acc Q02MG4
UniProtKB ID Q02MG4_PSEAB
UniRef100 UniRef100_S0IN70
UniRef50 UniRef50_G8QBH3
UniRef90 UniRef90_W0WHW2

Product

Feature Type CDS
Coding Frame 1
Product Name
ClpV3
Product Name Confidence: Class 1
CommentHcp Secretion Island-III-encoded type VI secretion system (H3-T6SS)
Evidence for Translation
Charge (pH 7) -22.01
Kyte-Doolittle Hydrophobicity Value -0.133
Molecular Weight (kDa) 92.5
Isoelectric Point (pI) 5.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-3 encoded type VI secretion system (H3-T6SS)
Evidence ECO:0000316
genetic interaction evidence used in manual assertion
Host Organism Arabidopsis thaliana
Notes
Infection model Arabidopsis leaf infiltration model
Reference 19497948

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 598 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000089 (1211 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_33990
Search term: clpV3
Search term: ClpV3

Human Homologs

Ensembl 86, assembly GRCh38.p7
ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]
E-value: 2.1e-29
Percent Identity: 39.3

References

Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.
Lesic B, Starkey M, He J, Hazan R, Rahme LG
Microbiology (Reading, Engl.) 2009 Sep;155(Pt 9):2845-55
PubMed ID: 19497948
PubMed ID: 28673999