Pseudomonas aeruginosa UCBPP-PA14, PA14_34010 (hsiG3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_34010
Name
hsiG3
Synonym: tssF3
Replicon chromosome
Genomic location 3024871 - 3026664 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs

Cross-References

RefSeq YP_790874.1
GI 116050309
Entrez 4380430
INSDC ABJ11545.1
NCBI Locus Tag PA14_34010
UniParc UPI0000396ABE
UniProtKB Acc Q02MG2
UniProtKB ID Q02MG2_PSEAB
UniRef100 UniRef100_Q02MG2
UniRef50 UniRef50_G8QBH5
UniRef90 UniRef90_W0YPX0

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiG3
Product Name Confidence: Class 1
CommentHcp Secretion Island-III-encoded type VI secretion system (H3-T6SS)
Evidence for Translation
Charge (pH 7) -8.12
Kyte-Doolittle Hydrophobicity Value -0.139
Molecular Weight (kDa) 65.8
Isoelectric Point (pI) 6.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-3 encoded type VI secretion system (H3-T6SS)
Evidence ECO:0000316
genetic interaction evidence used in manual assertion
Host Organism Arabidopsis thaliana
Notes
Infection model Arabidopsis leaf infiltration model
Reference 19497948

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 106 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000087 (1266 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_34010
Search term: hsiG3
Search term: HsiG3

References

Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.
Lesic B, Starkey M, He J, Hazan R, Rahme LG
Microbiology (Reading, Engl.) 2009 Sep;155(Pt 9):2845-55
PubMed ID: 19497948
The VgrG proteins are "à la carte" delivery systems for bacterial type VI effectors.
Hachani A, Allsopp LP, Oduko Y, Filloux A
J. Biol. Chem. 2014 Jun;289(25):17872-84
PubMed ID: 24794869