Pseudomonas aeruginosa UCBPP-PA14, PA14_34050 (hsiC3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_34050
Name
hsiC3
Replicon chromosome
Genomic location 3027657 - 3029141 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 8 transposon mutants in orthologs
CommentHcp Secretion Island-III-encoded type VI secretion system (H3-T6SS)

Cross-References

RefSeq YP_790877.1
GI 116050306
Entrez 4385125
INSDC ABJ11542.1
NCBI Locus Tag PA14_34050
UniParc UPI0000396ABC
UniProtKB Acc Q02MF9
UniProtKB ID Q02MF9_PSEAB
UniRef100 UniRef100_Q02MF9
UniRef50 UniRef50_B5E875
UniRef90 UniRef90_C1DM91

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiC3
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -9.42
Kyte-Doolittle Hydrophobicity Value -0.266
Molecular Weight (kDa) 55.0
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-3 encoded type VI secretion system (H3-T6SS)
Evidence ECO:0000316
genetic interaction evidence used in manual assertion
Host Organism Arabidopsis thaliana
Notes
Infection model Arabidopsis leaf infiltration model
Reference 19497948

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 111 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000083 (1277 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_34050
Search term: hsiC3
Search term: HsiC3

References

Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.
Lesic B, Starkey M, He J, Hazan R, Rahme LG
Microbiology (Reading, Engl.) 2009 Sep;155(Pt 9):2845-55
PubMed ID: 19497948
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999