Pseudomonas aeruginosa UCBPP-PA14, PA14_34070 (hsiB3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_34070
Name
hsiB3
Synonym: tssB3
Replicon chromosome
Genomic location 3029164 - 3029709 (- strand)
Transposon Mutants in orthologs 6 transposon mutants in orthologs
CommentHcp Secretion Island-III-encoded type VI secretion system (H3-T6SS)

Cross-References

RefSeq YP_790878.1
GI 116050305
Entrez 4385124
INSDC ABJ11541.1
NCBI Locus Tag PA14_34070
UniParc UPI00000C5691
UniProtKB Acc Q02MF8
UniProtKB ID Q02MF8_PSEAB
UniRef100 UniRef100_W0YSB1
UniRef50 UniRef50_W0YSB1
UniRef90 UniRef90_W0YSB1

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiB3
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -10.51
Kyte-Doolittle Hydrophobicity Value -0.517
Molecular Weight (kDa) 20.2
Isoelectric Point (pI) 4.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-3 encoded type VI secretion system (H3-T6SS)
Evidence ECO:0000316
genetic interaction evidence used in manual assertion
Host Organism Arabidopsis thaliana
Notes
Infection model Arabidopsis leaf infiltration model
Reference 19497948

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 109 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000082 (1276 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_34070
Search term: hsiB3
Search term: HsiB3

References

Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis.
Lesic B, Starkey M, He J, Hazan R, Rahme LG
Microbiology (Reading, Engl.) 2009 Sep;155(Pt 9):2845-55
PubMed ID: 19497948
The VgrG proteins are "à la carte" delivery systems for bacterial type VI effectors.
Hachani A, Allsopp LP, Oduko Y, Filloux A
J. Biol. Chem. 2014 Jun;289(25):17872-84
PubMed ID: 24794869