Pseudomonas aeruginosa PAO1, PA0336 (ygdP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0336
Name
ygdP
Replicon chromosome
Genomic location 378096 - 378575 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249027.1
GI 15595533
Affymetrix PA0336_at
Entrez 882290
GenBank AAG03725.1
INSDC AAG03725.1
NCBI Locus Tag PA0336
protein_id(GenBank) gb|AAG03725.1|AE004471_8|gnl|PseudoCAP|PA0336
TIGR NTL03PA00337
UniParc UPI0000130902
UniProtKB Acc Q9X4P2
UniProtKB ID RPPH_PSEAE
UniRef100 UniRef100_A6UYD9
UniRef50 UniRef50_A6UYD9
UniRef90 UniRef90_A6UYD9

Product

Feature Type CDS
Coding Frame 1
Product Name
Nudix hydrolase YgdP
Product Name Confidence: Class 2
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.17
Kyte-Doolittle Hydrophobicity Value -0.500
Molecular Weight (kDa) 18.7
Isoelectric Point (pI) 9.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 247 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000328 (558 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0336
Search term: ygdP

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 19146
Genomic Position 378366
Position in ORF 271(480)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 17472
Genomic Position 378568
Position in ORF 473(480)
Reference 14617778

Transposon Insertions in Orthologs

References

The gene ygdP, associated with the invasiveness of Escherichia coli K1, designates a Nudix hydrolase, Orf176, active on adenosine (5')-pentaphospho-(5')-adenosine (Ap5A).
Bessman MJ, Walsh JD, Dunn CA, Swaminathan J, Weldon JE, Shen J
J. Biol. Chem. 2001 Oct;276(41):37834-8
PubMed ID: 11479323