Pseudomonas aeruginosa PAO1, PA0789

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0789
Name
Replicon chromosome
Genomic location 864095 - 865510 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_249480.1
GI 15595986
Affymetrix PA0789_at
Entrez 879370
GenBank AAG04178.1
INSDC AAG04178.1
NCBI Locus Tag PA0789
protein_id(GenBank) gb|AAG04178.1|AE004514_1|gnl|PseudoCAP|PA0789
TIGR NTL03PA00790
UniParc UPI00000C5152
UniProtKB Acc Q9I5E9
UniProtKB ID Q9I5E9_PSEAE
UniRef100 UniRef100_W0YMC8
UniRef50 UniRef50_O34618
UniRef90 UniRef90_W0YMC8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable amino acid permease
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 10.82
Kyte-Doolittle Hydrophobicity Value 0.784
Molecular Weight (kDa) 51.4
Isoelectric Point (pI) 9.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 413 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000219 (3043 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0789

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326]
E-value: 8.1e-20
Percent Identity: 25.0

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A cryptic proline permease in Salmonella typhimurium.
Liao MK, Gort S, Maloy S
Microbiology (Reading) 1997 Sep;143 ( Pt 9):2903-2911
PubMed ID: 9308174