Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0870
|
Name |
phhC
Synonym: aspC Synonym: tyrB |
Replicon | chromosome |
Genomic location | 950962 - 952161 (- strand) |
Transposon Mutants | 5 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_249561.1 |
GI | 15596067 |
Affymetrix | PA0870_phhC_at |
DNASU | PaCD00006400 |
Entrez | 880839 |
GenBank | AAG04259.1 |
INSDC | AAG04259.1 |
NCBI Locus Tag | PA0870 |
protein_id(GenBank) | gb|AAG04259.1|AE004522_1|gnl|PseudoCAP|PA0870 |
TIGR | NTL03PA00871 |
UniParc | UPI000013195D |
UniProtKB Acc | P43336 |
UniProtKB ID | PHHC_PSEAE |
UniRef100 | UniRef100_P43336 |
UniRef50 | UniRef50_P43336 |
UniRef90 | UniRef90_P43336 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
aromatic amino acid aminotransferase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -5.28 |
Kyte-Doolittle Hydrophobicity Value | -0.018 |
Molecular Weight (kDa) | 43.3 |
Isoelectric Point (pI) | 6.24 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000837 (453 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0870
Search term: phhC
Search term: aromatic amino acid aminotransferase
|
Ensembl
110, assembly
GRCh38.p14
|
glutamic-oxaloacetic transaminase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28487]
E-value:
1.1e-33
Percent Identity:
26.7
|
Pseudomonas aeruginosa possesses homologues of mammalian phenylalanine hydroxylase and 4 alpha-carbinolamine dehydratase/DCoH as part of a three-component gene cluster.
Zhao G, Xia T, Song J, Jensen RA
Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1366-70
PubMed ID: 8108417
|
PhhC is an essential aminotransferase for aromatic amino acid catabolism in Pseudomonas aeruginosa.
Gu W, Song J, Bonner CA, Xie G, Jensen RA
Microbiology (Reading) 1998 Nov;144 ( Pt 11):3127-3134
PubMed ID: 9846749
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|