Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0927
|
Name |
ldhA
Synonym: ldhD |
Replicon | chromosome |
Genomic location | 1011983 - 1012972 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_249618.1 |
GI | 15596124 |
Affymetrix | PA0927_ldhA_at |
Entrez | 881895 |
GenBank | AAG04316.1 |
INSDC | AAG04316.1 |
NCBI Locus Tag | PA0927 |
protein_id(GenBank) | gb|AAG04316.1|AE004527_3|gnl|PseudoCAP|PA0927 |
TIGR | NTL03PA00928 |
UniParc | UPI00000C51C1 |
UniProtKB Acc | Q9I530 |
UniProtKB ID | Q9I530_PSEAE |
UniRef100 | UniRef100_Q9I530 |
UniRef50 | UniRef50_Q1IDM4 |
UniRef90 | UniRef90_Q9I530 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
D-lactate dehydrogenase (fermentative)
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -6.72 |
Kyte-Doolittle Hydrophobicity Value | 0.042 |
Molecular Weight (kDa) | 35.8 |
Isoelectric Point (pI) | 6.14 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5Z20 | OXIDOREDUCTASE | 12/28/17 | The ternary structure of D-lactate dehydrogenase from Pseudomonas aeruginosa with NADH and oxamate | Pseudomonas aeruginosa | 2.2 | X-RAY DIFFRACTION | 100.0 |
6ABJ | OXIDOREDUCTASE | 07/21/18 | The apo-structure of D-lactate dehydrogenase from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.86 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 640 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000893 (1006 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0927
Search term: ldhA
Search term: D-lactate dehydrogenase (fermentative)
|
Mutants of Escherichia coli deficient in the fermentative lactate dehydrogenase.
Mat-Jan F, Alam KY, Clark DP
J Bacteriol 1989 Jan;171(1):342-8
PubMed ID: 2644194
|
Characterization of twenty-six new heat shock genes of Escherichia coli.
Chuang SE, Blattner FR
J Bacteriol 1993 Aug;175(16):5242-52
PubMed ID: 8349564
|
The ldhA gene encoding the fermentative lactate dehydrogenase of Escherichia coli.
Bunch PK, Mat-Jan F, Lee N, Clark DP
Microbiology (Reading) 1997 Jan;143 ( Pt 1):187-195
PubMed ID: 9025293
|