Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0999
|
Name |
pqsD
Synonym: fabH1 |
Replicon | chromosome |
Genomic location | 1081942 - 1082955 (+ strand) |
Transposon Mutants | 4 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | both pqsC and pqsD are needed for quinolone signal biosynthesis |
Comment | Quinolone signal response |
RefSeq | NP_249690.1 |
GI | 15596196 |
Affymetrix | PA0999_fabH1_at |
DNASU | PaCD00006462 |
Entrez | 880625 |
GenBank | AAG04388.1 |
INSDC | AAA88446.1 |
NCBI Locus Tag | PA0999 |
protein_id(GenBank) | gb|AAG04388.1|AE004532_12|gnl|PseudoCAP|PA0999 |
TIGR | NTL03PA01000 |
UniParc | UPI000012A472 |
UniProtKB Acc | P20582 |
UniProtKB ID | PQSD_PSEAE |
UniRef100 | UniRef100_P20582 |
UniRef50 | UniRef50_P20582 |
UniRef90 | UniRef90_P20582 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
3-oxoacyl-[acyl-carrier-protein] synthase III
|
Synonyms |
beta-ketoacyl-ACP synthase III acetyl CoA ACP transacetylase |
Evidence for Translation | |
Charge (pH 7) | -9.53 |
Kyte-Doolittle Hydrophobicity Value | 0.072 |
Molecular Weight (kDa) | 36.4 |
Isoelectric Point (pI) | 5.34 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3H78 | TRANSFERASE | 04/24/09 | Crystal structure of Pseudomonas aeruginosa PqsD C112A mutant in complex with anthranilic acid | Pseudomonas aeruginosa PAO1 | 1.7 | X-RAY DIFFRACTION | 99.7 |
3H77 | TRANSFERASE | 04/24/09 | Crystal structure of Pseudomonas aeruginosa PqsD in a covalent complex with anthranilate | Pseudomonas aeruginosa PAO1 | 1.8 | X-RAY DIFFRACTION | 100.0 |
3H76 | TRANSFERASE | 04/24/09 | Crystal structure of PqsD, a key enzyme in Pseudomonas aeruginosa quinolone signal biosynthesis pathway | Pseudomonas aeruginosa PAO1 | 1.8 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 587 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000962 (605 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0999
Search term: pqsD
Search term: 3-oxoacyl-[acyl-carrier-protein] synthase III
|
Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications.
Essar DW, Eberly L, Hadero A, Crawford IP
J Bacteriol 1990 Feb;172(2):884-900
PubMed ID: 2153661
|
Isolation and characterization of the beta-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12.
Tsay JT, Oh W, Larson TJ, Jackowski S, Rock CO
J Biol Chem 1992 Apr 5;267(10):6807-14
PubMed ID: 1551888
|