Pseudomonas aeruginosa PAO1, PA1172 (napC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1172
Name
napC
Replicon chromosome
Genomic location 1272200 - 1272796 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_249863.1
GI 15596369
Affymetrix PA1172_napC_at
DNASU PaCD00006539
Entrez 880706
GenBank AAG04561.1
INSDC AAG04561.1
NCBI Locus Tag PA1172
protein_id(GenBank) gb|AAG04561.1|AE004547_7|gnl|PseudoCAP|PA1172
TIGR NTL03PA01173
UniParc UPI00000C528A
UniProtKB Acc Q9I4G5
UniProtKB ID Q9I4G5_PSEAE
UniRef100 UniRef100_W0YMA0
UniRef50 UniRef50_Q53178
UniRef90 UniRef90_A6V926

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c-type protein NapC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 7.63
Kyte-Doolittle Hydrophobicity Value -0.322
Molecular Weight (kDa) 22.7
Isoelectric Point (pI) 8.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 97 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001130 (348 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1172
Search term: napC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The napEDABC gene cluster encoding the periplasmic nitrate reductase system of Thiosphaera pantotropha.
Berks BC, Richardson DJ, Reilly A, Willis AC, Ferguson SJ
Biochem J 1995 Aug 1;309 ( Pt 3)(Pt 3):983-92
PubMed ID: 7639719
Isolation of periplasmic nitrate reductase genes from Rhodobacter sphaeroides DSM 158: structural and functional differences among prokaryotic nitrate reductases.
Reyes F, Roldán MD, Klipp W, Castillo F, Moreno-Vivián C
Mol Microbiol 1996 Mar;19(6):1307-18
PubMed ID: 8730872