Pseudomonas aeruginosa PAO1, PA1196 (ddaR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1196
Name
ddaR
Replicon chromosome
Genomic location 1297309 - 1298709 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249887.1
GI 15596393
Affymetrix PA1196_at
Entrez 878419
GenBank AAG04585.1
INSDC AAG04585.1
NCBI Locus Tag PA1196
protein_id(GenBank) gb|AAG04585.1|AE004550_1|gnl|PseudoCAP|PA1196
TIGR NTL03PA01197
UniParc UPI00000C529F
UniProtKB Acc Q9I4E2
UniProtKB ID Q9I4E2_PSEAE
UniRef100 UniRef100_W0YNM0
UniRef50 UniRef50_Z2DIN3
UniRef90 UniRef90_Z2DIN3

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator DdaR
Product Name Confidence: Class 1
Synonyms probable transcriptional regulator
Evidence for Translation
Charge (pH 7) -0.99
Kyte-Doolittle Hydrophobicity Value -0.043
Molecular Weight (kDa) 50.2
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 452 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001154 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1196
Search term: ddaR

Human Homologs

References

DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
Lundgren BR, Bailey FJ, Moley G, Nomura CT
J Bacteriol 2017 Apr 15;199(8)
PubMed ID: 28167521