Pseudomonas aeruginosa PAO1, PA1429

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1429
Name
Replicon chromosome
Genomic location 1555012 - 1557720 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250120.1
GI 15596626
Affymetrix PA1429_at
Entrez 881803
GenBank AAG04818.1
INSDC AAG04818.1
NCBI Locus Tag PA1429
protein_id(GenBank) gb|AAG04818.1|AE004572_6|gnl|PseudoCAP|PA1429
TIGR NTL03PA01430
UniParc UPI00000C537A
UniProtKB Acc Q9I3R5
UniProtKB ID Q9I3R5_PSEAE
UniRef100 UniRef100_Q9I3R5
UniRef50 UniRef50_Q1LL86
UniRef90 UniRef90_W0WGC9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable cation-transporting P-type ATPase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -12.15
Kyte-Doolittle Hydrophobicity Value 0.278
Molecular Weight (kDa) 97.0
Isoelectric Point (pI) 5.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 639 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001347 (772 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1429

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATPase secretory pathway Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:13211]
E-value: 4.4e-139
Percent Identity: 36.7
Ensembl 110, assembly GRCh38.p14
ATPase secretory pathway Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:13211]
E-value: 4.4e-139
Percent Identity: 36.7

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG
Nature 1998 Jun 11;393(6685):537-44
PubMed ID: 9634230