Pseudomonas aeruginosa PAO1, PA1476 (ccmB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1476
Name
ccmB
Synonym: helB
Synonym: cyt10
Synonym: cycW
Replicon chromosome
Genomic location 1602877 - 1603548 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250167.1
GI 15596673
Affymetrix PA1476_ccmB_at
DNASU PaCD00006680
Entrez 880948
GenBank AAG04865.1
INSDC AAG04865.1
NCBI Locus Tag PA1476
protein_id(GenBank) gb|AAG04865.1|AE004576_14|gnl|PseudoCAP|PA1476
TIGR NTL03PA01477
UniParc UPI00000C5397
UniProtKB Acc Q9I3N6
UniProtKB ID CCMB_PSEAE
UniRef100 UniRef100_Q9I3N6
UniRef50 UniRef50_Q9I3N6
UniRef90 UniRef90_Q9I3N6

Product

Feature Type CDS
Coding Frame 1
Product Name
heme exporter protein CcmB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 1.68
Kyte-Doolittle Hydrophobicity Value 1.236
Molecular Weight (kDa) 23.4
Isoelectric Point (pI) 8.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 191 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001391 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1476
Search term: ccmB

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295