Pseudomonas aeruginosa PAO1, PA1532 (dnaX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1532
Name
dnaX
Replicon chromosome
Genomic location 1669989 - 1672034 (+ strand)

Cross-References

RefSeq NP_250223.1
GI 15596729
Affymetrix PA1532_dnaX_at
Entrez 883094
GenBank AAG04921.1
INSDC AAG04921.1
NCBI Locus Tag PA1532
protein_id(GenBank) gb|AAG04921.1|AE004581_8|gnl|PseudoCAP|PA1532
TIGR NTL03PA01533
UniParc UPI00000C53C9
UniProtKB Acc Q9I3I1
UniProtKB ID Q9I3I1_PSEAE
UniRef100 UniRef100_Q9I3I1
UniRef50 UniRef50_Q9I3I1
UniRef90 UniRef90_Q9I3I1

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA polymerase subunits gamma and tau
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -40.54
Kyte-Doolittle Hydrophobicity Value -0.135
Molecular Weight (kDa) 73.3
Isoelectric Point (pI) 4.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 663 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003827 (527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1532
Search term: dnaX

Human Homologs

References

Programmed ribosomal frameshifting generates the Escherichia coli DNA polymerase III gamma subunit from within the tau subunit reading frame.
Blinkowa AL, Walker JR
Nucleic Acids Res 1990 Apr 11;18(7):1725-9
PubMed ID: 2186364
The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting.
Flower AM, McHenry CS
Proc Natl Acad Sci U S A 1990 May;87(10):3713-7
PubMed ID: 2187190