Pseudomonas aeruginosa PAO1, PA1582 (sdhD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1582
Name
sdhD
Replicon chromosome
Genomic location 1721124 - 1721492 (+ strand)

Cross-References

RefSeq NP_250273.1
GI 15596779
Affymetrix PA1582_sdhD_at
DNASU PaCD00006724
Entrez 881923
GenBank AAG04971.1
INSDC AAG04971.1
NCBI Locus Tag PA1582
protein_id(GenBank) gb|AAG04971.1|AE004586_9|gnl|PseudoCAP|PA1582
TIGR NTL03PA01583
UniParc UPI00000C53F1
UniProtKB Acc Q9I3D6
UniProtKB ID Q9I3D6_PSEAE
UniRef100 UniRef100_W0Z4T8
UniRef50 UniRef50_W6R327
UniRef90 UniRef90_A6V7L1

Product

Feature Type CDS
Coding Frame 1
Product Name
succinate dehydrogenase (D subunit)
Product Name Confidence: Class 2
Synonyms succinate dehydrogenase hydrophobic membrane anchor protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.66
Kyte-Doolittle Hydrophobicity Value 0.906
Molecular Weight (kDa) 13.7
Isoelectric Point (pI) 9.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 108 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003781 (539 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1582
Search term: sdhD

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence encoding the flavoprotein and hydrophobic subunits of the succinate dehydrogenase of Escherichia coli.
Wood D, Darlison MG, Wilde RJ, Guest JR
Biochem J 1984 Sep 1;222(2):519-34
PubMed ID: 6383359
Transcript analysis of the citrate synthase and succinate dehydrogenase genes of Escherichia coli K12.
Wilde RJ, Guest JR
J Gen Microbiol 1986 Dec;132(12):3239-51
PubMed ID: 3309132