Pseudomonas aeruginosa PAO1, PA1648

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA1648
Name
Replicon	chromosome
Genomic location	1794883 - 1795887 (- strand)
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_250339.1
GI	15596845
Affymetrix	PA1648_at
Entrez	882158
GenBank	AAG05037.1
INSDC	AAG05037.1
NCBI Locus Tag	PA1648
protein_id(GenBank)	gb|AAG05037.1|AE004592_8|gnl|PseudoCAP|PA1648
TIGR	NTL03PA01649
UniParc	UPI00000C5426
UniProtKB Acc	Q9I377
UniProtKB ID	Q9I377_PSEAE
UniRef100	UniRef100_W0YRQ8
UniRef50	UniRef50_C9YGX1
UniRef90	UniRef90_A0A077JVR2

Product

Feature Type	CDS
Coding Frame	1
Product Name	probable oxidoreductase Product Name Confidence: Class 3
Synonyms
Evidence for Translation	Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7)	-0.88
Kyte-Doolittle Hydrophobicity Value	-0.037
Molecular Weight (kDa)	36.2
Isoelectric Point (pI)	6.11

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4B7C	OXIDOREDUCTASE	08/17/12	Crystal structure of hypothetical protein PA1648 from Pseudomonas aeruginosa.	PSEUDOMONAS AERUGINOSA PA01	2.1	X-RAY DIFFRACTION	100.0
4B7X	OXIDOREDUCTASE	08/24/12	Crystal structure of hypothetical protein PA1648 from Pseudomonas aeruginosa.	PSEUDOMONAS AERUGINOSA PAO1	2.2	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 427 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003726 (526 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA1648 Search term: probable oxidoreductase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000452280 prostaglandin reductase 2 [Source:HGNC Symbol;Acc:HGNC:20149] E-value: 4.2e-55 Percent Identity: 38.1
Ensembl 110, assembly GRCh38.p14	ENSP00000267568 prostaglandin reductase 2 [Source:HGNC Symbol;Acc:HGNC:20149] E-value: 4.2e-55 Percent Identity: 38.1
Ensembl 110, assembly GRCh38.p14	ENSP00000450975 prostaglandin reductase 2 [Source:HGNC Symbol;Acc:HGNC:20149] E-value: 4.2e-55 Percent Identity: 38.1

References