Pseudomonas aeruginosa PAO1, PA1660 (hsiG2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1660
Name
hsiG2
Replicon chromosome
Genomic location 1808193 - 1809773 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_250351.1
GI 15596857
Affymetrix PA1660_at
Entrez 880603
GenBank AAG05049.1
INSDC AAG05049.1
NCBI Locus Tag PA1660
protein_id(GenBank) gb|AAG05049.1|AE004594_1|gnl|PseudoCAP|PA1660
TIGR NTL03PA01661
UniParc UPI00000C5432
UniProtKB Acc Q9I365
UniProtKB ID Q9I365_PSEAE
UniRef100 UniRef100_Q9I365
UniRef50 UniRef50_Q9I365
UniRef90 UniRef90_Q9I365

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiG2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.65
Kyte-Doolittle Hydrophobicity Value -0.156
Molecular Weight (kDa) 59.7
Isoelectric Point (pI) 6.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-2 encoded type VI secretion system (H2-T6SS)
Evidence ECO:0000317
genomic context evidence used in manual assertion
Host Organism Homo sapiens
Notes H2-T6SS rendered inactive via clpV2 deletion.
Reference 22665491

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 104 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000087 (1217 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1660
Search term: hsiG2
Search term: HsiG2

Human Homologs

References

No references are associated with this feature.