Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1843
|
Name |
metH
|
Replicon | chromosome |
Genomic location | 1999889 - 2003593 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250534.1 |
GI | 15597040 |
Affymetrix | PA1843_metH_at |
Entrez | 880631 |
GenBank | AAG05232.1 |
INSDC | AAG05232.1 |
NCBI Locus Tag | PA1843 |
protein_id(GenBank) | gb|AAG05232.1|AE004610_5|gnl|PseudoCAP|PA1843 |
TIGR | NTL03PA01844 |
UniParc | UPI00000C54C7 |
UniProtKB Acc | Q9I2Q2 |
UniProtKB ID | METH_PSEAE |
UniRef100 | UniRef100_Q9I2Q2 |
UniRef50 | UniRef50_P13009 |
UniRef90 | UniRef90_Q9I2Q2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
methionine synthase
|
Synonyms |
5-methyltetrahydrofolate--homocysteine S-methyltransferase |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -53.05 |
Kyte-Doolittle Hydrophobicity Value | -0.154 |
Molecular Weight (kDa) | 135.1 |
Isoelectric Point (pI) | 4.62 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 504 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003557 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1843
Search term: metH
Search term: methionine synthase
|
Ensembl
110, assembly
GRCh38.p14
|
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value:
0.0e+00
Percent Identity:
54.5
|
Ensembl
110, assembly
GRCh38.p14
|
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value:
0.0e+00
Percent Identity:
54.8
|
Ensembl
110, assembly
GRCh38.p14
|
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value:
0.0e+00
Percent Identity:
52.3
|
Ensembl
110, assembly
GRCh38.p14
|
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value:
0.0e+00
Percent Identity:
51.2
|
Ensembl
110, assembly
GRCh38.p14
|
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value:
0.0e+00
Percent Identity:
52.4
|
Cloning and sequence analysis of the Escherichia coli metH gene encoding cobalamin-dependent methionine synthase and isolation of a tryptic fragment containing the cobalamin-binding domain.
Banerjee RV, Johnston NL, Sobeski JK, Datta P, Matthews RG
J Biol Chem 1989 Aug 15;264(23):13888-95
PubMed ID: 2668277
|
Cobalamin-dependent methionine synthase.
Banerjee RV, Matthews RG
FASEB J 1990 Mar;4(5):1450-9
PubMed ID: 2407589
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|