Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1865
|
Name |
Synonym: FAN1 |
Replicon | chromosome |
Genomic location | 2024065 - 2025744 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250556.1 |
GI | 15597062 |
Affymetrix | PA1865_at |
Entrez | 877940 |
GenBank | AAG05254.1 |
INSDC | AAG05254.1 |
NCBI Locus Tag | PA1865 |
protein_id(GenBank) | gb|AAG05254.1|AE004612_8|gnl|PseudoCAP|PA1865 |
TIGR | NTL03PA01866 |
UniParc | UPI00000C54DD |
UniProtKB Acc | Q9I2N0 |
UniProtKB ID | FAN1_PSEAE |
UniRef100 | UniRef100_Q9I2N0 |
UniRef50 | UniRef50_Q9I2N0 |
UniRef90 | UniRef90_Q9I2N0 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Fanconi anemia-associated nuclease 1
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -11.02 |
Kyte-Doolittle Hydrophobicity Value | -0.288 |
Molecular Weight (kDa) | 64.5 |
Isoelectric Point (pI) | 5.67 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4R89 | Hydrolase/DNA | 08/30/14 | Crystal structure of paFAN1 - 5' flap DNA complex with Manganase | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 4.002 | X-RAY DIFFRACTION | 100.0 |
4R8A | Hydrolase/DNA | 08/30/14 | Crystal structure of paFAN1 - 5' flap DNA complex | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 3.2 | X-RAY DIFFRACTION | 100.0 |
5Y7G | HYDROLASE/DNA | 08/17/17 | Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 3.4 | X-RAY DIFFRACTION | 100.0 |
5Z6W | HYDROLASE/DNA | 01/25/18 | Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap with Manganese | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 3.2 | X-RAY DIFFRACTION | 100.0 |
5Y7Q | HYDROLASE/DNA | 08/17/17 | Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 2.7 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 34 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003538 (532 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1865
Search term: Fanconi anemia-associated nuclease 1
|
Ensembl
110, assembly
GRCh38.p14
|
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value:
4.5e-17
Percent Identity:
32.3
|
Ensembl
110, assembly
GRCh38.p14
|
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value:
4.5e-17
Percent Identity:
32.3
|
Ensembl
110, assembly
GRCh38.p14
|
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value:
4.5e-17
Percent Identity:
32.3
|
Ensembl
110, assembly
GRCh38.p14
|
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value:
4.5e-17
Percent Identity:
32.3
|
Ensembl
110, assembly
GRCh38.p14
|
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value:
4.5e-17
Percent Identity:
32.3
|
Ensembl
110, assembly
GRCh38.p14
|
FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170]
E-value:
4.5e-17
Percent Identity:
32.3
|
Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.
Gwon GH, Kim Y, Liu Y, Watson AT, Jo A, Etheridge TJ, Yuan F, Zhang Y, Kim Y, Carr AM, Cho Y
Genes Dev 2014 Oct 15;28(20):2276-90
PubMed ID: 25319828
|