Pseudomonas aeruginosa PAO1, PA1877

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1877
Name
Replicon chromosome
Genomic location 2047275 - 2048462 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Commentinvolved in biofilm-specific resistance to a subset of antibiotics

Cross-References

RefSeq NP_250568.1
GI 15597074
Affymetrix PA1877_at
Entrez 883045
GenBank AAG05266.1
INSDC AAG05266.1
NCBI Locus Tag PA1877
protein_id(GenBank) gb|AAG05266.1|AE004613_11|gnl|PseudoCAP|PA1877
TIGR NTL03PA01878
UniParc UPI00000C54E6
UniProtKB Acc Q9I2M0
UniProtKB ID Q9I2M0_PSEAE
UniRef100 UniRef100_W0YNA9
UniRef50 UniRef50_A6F3W2
UniRef90 UniRef90_W0YNA9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable secretion protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.71
Kyte-Doolittle Hydrophobicity Value -0.198
Molecular Weight (kDa) 44.2
Isoelectric Point (pI) 7.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 255 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003529 (469 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1877

Human Homologs

References

The 32-kilobase exp gene cluster of Rhizobium meliloti directing the biosynthesis of galactoglucan: genetic organization and properties of the encoded gene products.
Becker A, Rüberg S, Küster H, Roxlau AA, Keller M, Ivashina T, Cheng HP, Walker GC, Pühler A
J Bacteriol 1997 Feb;179(4):1375-84
PubMed ID: 9023225