Pseudomonas aeruginosa PAO1, PA2022

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2022
Name
Replicon chromosome
Genomic location 2213693 - 2215054 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250712.1
GI 15597218
Affymetrix PA2022_at
Entrez 879866
GenBank AAG05410.1
INSDC AAG05410.1
NCBI Locus Tag PA2022
protein_id(GenBank) gb|AAG05410.1|AE004628_8|gnl|PseudoCAP|PA2022
TIGR NTL03PA02022
UniParc UPI0000137AA6
UniProtKB Acc O86422
UniProtKB ID UDG_PSEAE
UniRef100 UniRef100_O86422
UniRef50 UniRef50_O86422
UniRef90 UniRef90_O86422

Product

Feature Type CDS
Coding Frame 1
Product Name
probable nucleotide sugar dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 8.40
Kyte-Doolittle Hydrophobicity Value -0.104
Molecular Weight (kDa) 49.7
Isoelectric Point (pI) 8.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002107 (812 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2022

Human Homologs

References

Properties and kinetic analysis of UDP-glucose dehydrogenase from group A streptococci. Irreversible inhibition by UDP-chloroacetol.
Campbell RE, Sala RF, van de Rijn I, Tanner ME
J Biol Chem 1997 Feb 7;272(6):3416-22
PubMed ID: 9013585
Novel rkp gene clusters of Sinorhizobium meliloti involved in capsular polysaccharide production and invasion of the symbiotic nodule: the rkpK gene encodes a UDP-glucose dehydrogenase.
Kereszt A, Kiss E, Reuhs BL, Carlson RW, Kondorosi A, Putnoky P
J Bacteriol 1998 Oct;180(20):5426-31
PubMed ID: 9765575