Pseudomonas aeruginosa PAO1, PA2220

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2220
Name
Synonym: oprR
Replicon chromosome
Genomic location 2441771 - 2442691 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250910.1
GI 15597416
Affymetrix PA2220_at
DNASU PaCD00006987
Entrez 879199
GenBank AAG05608.1
INSDC CAA78445.1
NCBI Locus Tag PA2220
protein_id(GenBank) gb|AAG05608.1|AE004648_7|gnl|PseudoCAP|PA2220
TIGR NTL03PA02220
UniParc UPI0000130DA1
UniProtKB Acc Q01610
UniProtKB ID OPRR_PSEAE
UniRef100 UniRef100_Q01610
UniRef50 UniRef50_P77333
UniRef90 UniRef90_Q01610

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transcriptional regulator
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.11
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 34.0
Isoelectric Point (pI) 8.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 462 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001088 (834 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2220

Human Homologs

References

Analysis of two gene regions involved in the expression of the imipenem-specific, outer membrane porin protein OprD of Pseudomonas aeruginosa.
Huang H, Siehnel RJ, Bellido F, Rawling E, Hancock RE
FEMS Microbiol Lett 1992 Oct 15;76(3):267-73
PubMed ID: 1427017