Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2247
|
Name |
bkdA1
|
Replicon | chromosome |
Genomic location | 2473213 - 2474445 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_250937.1 |
GI | 15597443 |
Affymetrix | PA2247_bkdA1_at |
Entrez | 877901 |
GenBank | AAG05635.1 |
INSDC | AAG05635.1 |
NCBI Locus Tag | PA2247 |
protein_id(GenBank) | gb|AAG05635.1|AE004650_6|gnl|PseudoCAP|PA2247 |
TIGR | NTL03PA02247 |
UniParc | UPI00000D74B0 |
UniProtKB Acc | Q9I1M2 |
UniProtKB ID | ODBA_PSEAE |
UniRef100 | UniRef100_Q9I1M2 |
UniRef50 | UniRef50_P09060 |
UniRef90 | UniRef90_Q9I1M2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
2-oxoisovalerate dehydrogenase (alpha subunit)
|
Synonyms |
branched-chain alpha-keto acid decarboxylase 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -7.25 |
Kyte-Doolittle Hydrophobicity Value | -0.286 |
Molecular Weight (kDa) | 45.3 |
Isoelectric Point (pI) | 5.94 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 421 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002213 (788 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2247
Search term: bkdA1
Search term: 2-oxoisovalerate dehydrogenase (alpha subunit)
|
Molecular cloning of genes encoding branched-chain keto acid dehydrogenase of Pseudomonas putida.
Sykes PJ, Burns G, Menard J, Hatter K, Sokatch JR
J Bacteriol 1987 Apr;169(4):1619-25
PubMed ID: 3549697
|
Similarity of the E1 subunits of branched-chain-oxoacid dehydrogenase from Pseudomonas putida to the corresponding subunits of mammalian branched-chain-oxoacid and pyruvate dehydrogenases.
Burns G, Brown T, Hatter K, Idriss JM, Sokatch JR
Eur J Biochem 1988 Sep 15;176(2):311-7
PubMed ID: 3416875
|
Transcriptional analysis of the promoter region of the Pseudomonas putida branched-chain keto acid dehydrogenase operon.
Madhusudhan KT, Huang G, Burns G, Sokatch JR
J Bacteriol 1990 Oct;172(10):5655-63
PubMed ID: 2211503
|