Pseudomonas aeruginosa PAO1, PA2263

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2263
Name
Synonym: kguD
Synonym: yiaE
Replicon chromosome
Genomic location 2492064 - 2493050 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250953.1
GI 15597459
Affymetrix PA2263_at
Entrez 877698
GenBank AAG05651.1
INSDC AAG05651.1
NCBI Locus Tag PA2263
protein_id(GenBank) gb|AAG05651.1|AE004652_4|gnl|PseudoCAP|PA2263
TIGR NTL03PA02263
UniParc UPI00000C6EB1
UniProtKB Acc Q9I1L0
UniProtKB ID Q9I1L0_PSEAE
UniRef100 UniRef100_G3XCL1
UniRef50 UniRef50_G8QCF7
UniRef90 UniRef90_V8E0E5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable 2-hydroxyacid dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.87
Kyte-Doolittle Hydrophobicity Value -0.006
Molecular Weight (kDa) 35.6
Isoelectric Point (pI) 8.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003228 (470 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2263

Human Homologs

Ensembl 94, assembly GRCh38.p12
glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570]
E-value: 5.5e-48
Percent Identity: 43.7

References

No references are associated with this feature.