Pseudomonas aeruginosa PAO1, PA2492 (mexT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2492
Name
mexT
Replicon chromosome
Genomic location 2807469 - 2808512 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251182.1
GI 15597688
Affymetrix PA2492_mexT_at
Entrez 880417
GenBank AAG05880.1
NCBI Locus Tag PA2492
protein_id(GenBank) gb|AAG05880.1|AE004676_12|gnl|PseudoCAP|PA2492
TIGR NTL03PA02492
UniProtKB Acc Q9I0Z0
UniProtKB ID Q9I0Z0_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator MexT
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.19
Kyte-Doolittle Hydrophobicity Value -0.405
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 10.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 185 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001179 (2011 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2492
Search term: mexT

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 8076
Genomic Position 2807624
Position in ORF 156(1044)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 8280
Genomic Position 2807624
Position in ORF 156(1044)
Reference 14617778

Transposon Insertions in Orthologs

References

Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa.
Köhler T, Michéa-Hamzehpour M, Henze U, Gotoh N, Curty LK, Pechère JC
Mol. Microbiol. 1997 Jan;23(2):345-54
PubMed ID: 9044268
MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa.
Jin Y, Yang H, Qiao M, Jin S
J. Bacteriol. 2011 Jan;193(2):399-410
PubMed ID: 21075931