Pseudomonas aeruginosa PAO1, PA2617 (aat)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2617
Name
aat
Replicon chromosome
Genomic location 2960456 - 2961136 (+ strand)

Cross-References

RefSeq NP_251307.1
GI 15597813
Affymetrix PA2617_aat_at
DNASU PaCD00007128
Entrez 882323
GenBank AAG06005.1
INSDC AAG06005.1
NCBI Locus Tag PA2617
protein_id(GenBank) gb|AAG06005.1|AE004690_5|gnl|PseudoCAP|PA2617
TIGR NTL03PA02617
UniParc UPI00000C576D
UniProtKB Acc Q9I0M1
UniProtKB ID LFTR_PSEAE
UniRef100 UniRef100_Q9I0M1
UniRef50 UniRef50_Q9I0M1
UniRef90 UniRef90_Q9I0M1

Product

Feature Type CDS
Coding Frame 1
Product Name
leucyl/phenylalanyl-tRNA-protein transferase
Product Name Confidence: Class 2
Synonyms leucyltransferase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.55
Kyte-Doolittle Hydrophobicity Value -0.279
Molecular Weight (kDa) 25.8
Isoelectric Point (pI) 7.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 330 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002935 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2617
Search term: aat

Human Homologs

References

The N-end rule in Escherichia coli: cloning and analysis of the leucyl, phenylalanyl-tRNA-protein transferase gene aat.
Shrader TE, Tobias JW, Varshavsky A
J Bacteriol 1993 Jul;175(14):4364-74
PubMed ID: 8331068