Pseudomonas aeruginosa PAO1, PA2638 (nuoB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2638
Name
nuoB
Replicon chromosome
Genomic location 2983205 - 2983882 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251328.1
GI 15597834
Affymetrix PA2638_nuoB_at
Entrez 882345
GenBank AAG06026.1
INSDC AAG06026.1
NCBI Locus Tag PA2638
protein_id(GenBank) gb|AAG06026.1|AE004692_5|gnl|PseudoCAP|PA2638
TIGR NTL03PA02638
UniParc UPI00000C577F
UniProtKB Acc Q9I0K0
UniProtKB ID NUOB_PSEAE
UniRef100 UniRef100_B7VAR4
UniRef50 UniRef50_Q4K9T5
UniRef90 UniRef90_Q4K9T5

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase I chain B
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.68
Kyte-Doolittle Hydrophobicity Value -0.238
Molecular Weight (kDa) 25.4
Isoelectric Point (pI) 5.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 505 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002915 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2638
Search term: nuoB

Human Homologs

Ensembl 110, assembly GRCh38.p14
NADH:ubiquinone oxidoreductase core subunit S7 [Source:HGNC Symbol;Acc:HGNC:7714]
E-value: 1.6e-42
Percent Identity: 55.2

References

The gene locus of the proton-translocating NADH: ubiquinone oxidoreductase in Escherichia coli. Organization of the 14 genes and relationship between the derived proteins and subunits of mitochondrial complex I.
Weidner U, Geier S, Ptock A, Friedrich T, Leif H, Weiss H
J Mol Biol 1993 Sep 5;233(1):109-22
PubMed ID: 7690854