Pseudomonas aeruginosa PAO1, PA2652

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2652
Name
Replicon chromosome
Genomic location 3000074 - 3001759 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_251342.1
GI 15597848
Affymetrix PA2652_at
Entrez 882361
GenBank AAG06040.1
NCBI Locus Tag PA2652
protein_id(GenBank) gb|AAG06040.1|AE004694_3|gnl|PseudoCAP|PA2652
TIGR NTL03PA02652
UniProtKB Acc Q9I0I6
UniProtKB ID Q9I0I6_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
methyl-accepting chemotaxis protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -14.80
Kyte-Doolittle Hydrophobicity Value -0.124
Molecular Weight (kDa) 60.3
Isoelectric Point (pI) 4.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 406 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002657 (1774 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2652

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Genetic identification of chemotactic transducers for amino acids in Pseudomonas aeruginosa.
Taguchi K, Fukutomi H, Kuroda A, Kato J, Ohtake H
Microbiology (Reading) 1997 Oct;143 ( Pt 10):3223-3229
PubMed ID: 9353923
Identification of a malate chemoreceptor in Pseudomonas aeruginosa by screening for chemotaxis defects in an energy taxis-deficient mutant.
Alvarez-Ortega C, Harwood CS
Appl Environ Microbiol 2007 Dec;73(23):7793-5
PubMed ID: 17933940
The activity of the C4-dicarboxylic acid chemoreceptor of Pseudomonas aeruginosa is controlled by chemoattractants and antagonists.
Martín-Mora D, Ortega Á, Pérez-Maldonado FJ, Krell T, Matilla MA
Sci Rep 2018 Feb 1;8(1):2102
PubMed ID: 29391435