Pseudomonas aeruginosa PAO1, PA2796 (tal)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2796
Name
tal
Replicon chromosome
Genomic location 3153582 - 3154505 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_251486.1
GI 15597992
Affymetrix PA2796_tal_at
DNASU PaCD00007214
Entrez 882755
GenBank AAG06184.1
INSDC AAG06184.1
NCBI Locus Tag PA2796
protein_id(GenBank) gb|AAG06184.1|AE004707_3|gnl|PseudoCAP|PA2796
TIGR NTL03PA02796
UniParc UPI00001368B9
UniProtKB Acc Q9I047
UniProtKB ID TAL_PSEAE
UniRef100 UniRef100_Q02NV3
UniRef50 UniRef50_Q6MAI4
UniRef90 UniRef90_Q02NV3

Product

Feature Type CDS
Coding Frame 1
Product Name
transaldolase
Product Name Confidence: Class 2
Synonyms dihydroxyacetone transferase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.36
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 33.9
Isoelectric Point (pI) 4.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 514 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002773 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2796
Search term: tal
Search term: transaldolase

Human Homologs

Ensembl 110, assembly GRCh38.p14
transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559]
E-value: 1.2e-88
Percent Identity: 57.4

References

Transaldolase B of Escherichia coli K-12: cloning of its gene, talB, and characterization of the enzyme from recombinant strains.
Sprenger GA, Schörken U, Sprenger G, Sahm H
J Bacteriol 1995 Oct;177(20):5930-6
PubMed ID: 7592346
Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family.
Jia J, Huang W, Schörken U, Sahm H, Sprenger GA, Lindqvist Y, Schneider G
Structure 1996 Jun 15;4(6):715-24
PubMed ID: 8805555