Pseudomonas aeruginosa PAO1, PA2969 (plsX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2969
Name
plsX
Replicon chromosome
Genomic location 3327189 - 3328169 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251659.1
GI 15598165
Affymetrix PA2969_plsX_at
Entrez 880143
GenBank AAG06357.1
INSDC AAG06357.1
NCBI Locus Tag PA2969
protein_id(GenBank) gb|AAG06357.1|AE004723_1|gnl|PseudoCAP|PA2969
TIGR NTL03PA02969
UniParc UPI0000131C6B
UniProtKB Acc Q9HZN5
UniProtKB ID PLSX_PSEAE
UniRef100 UniRef100_Q02PD2
UniRef50 UniRef50_Q02PD2
UniRef90 UniRef90_Q02PD2

Product

Feature Type CDS
Coding Frame 1
Product Name
fatty acid biosynthesis protein PlsX
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 3.22
Kyte-Doolittle Hydrophobicity Value 0.106
Molecular Weight (kDa) 34.6
Isoelectric Point (pI) 7.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 463 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002613 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2969
Search term: plsX

Human Homologs

References

sn-Glycerol-3-phosphate auxotrophy of plsB strains of Escherichia coli: evidence that a second mutation, plsX, is required.
Larson TJ, Ludtke DN, Bell RM
J Bacteriol 1984 Nov;160(2):711-7
PubMed ID: 6094487
Transcriptional analysis of essential genes of the Escherichia coli fatty acid biosynthesis gene cluster by functional replacement with the analogous Salmonella typhimurium gene cluster.
Zhang Y, Cronan JE Jr
J Bacteriol 1998 Jul;180(13):3295-303
PubMed ID: 9642179