Pseudomonas aeruginosa PAO1, PA3000 (aroP1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3000
Name
aroP1
Replicon chromosome
Genomic location 3357758 - 3359167 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_251690.1
GI 15598196
Affymetrix PA3000_aroP1_at
Entrez 880559
GenBank AAG06388.1
INSDC AAG06388.1
NCBI Locus Tag PA3000
protein_id(GenBank) gb|AAG06388.1|AE004725_1|gnl|PseudoCAP|PA3000
TIGR NTL03PA03000
UniParc UPI00000C58BE
UniProtKB Acc Q9HZK5
UniProtKB ID Q9HZK5_PSEAE
UniRef100 UniRef100_Q9HZK5
UniRef50 UniRef50_Q9HZK5
UniRef90 UniRef90_Q9HZK5

Product

Feature Type CDS
Coding Frame 1
Product Name
aromatic amino acid transport protein AroP1
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 8.54
Kyte-Doolittle Hydrophobicity Value 0.771
Molecular Weight (kDa) 51.0
Isoelectric Point (pI) 9.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 348 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000833 (831 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3000
Search term: aroP1

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A topological model for the general aromatic amino acid permease, AroP, of Escherichia coli.
Cosgriff AJ, Pittard AJ
J Bacteriol 1997 May;179(10):3317-23
PubMed ID: 9150230