Pseudomonas aeruginosa PAO1, PA3006 (psrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3006
Name
psrA
Replicon chromosome
Genomic location 3366970 - 3367671 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251696.1
GI 15598202
Affymetrix PA3006_at
DNASU PaCD00007326
Entrez 879874
GenBank AAG06394.1
INSDC AAG06394.1
NCBI Locus Tag PA3006
protein_id(GenBank) gb|AAG06394.1|AE004725_7|gnl|PseudoCAP|PA3006
TIGR NTL03PA03006
UniParc UPI00000C58C3
UniProtKB Acc Q9HZJ9
UniProtKB ID Q9HZJ9_PSEAE
UniRef100 UniRef100_Q9HZJ9
UniRef50 UniRef50_Q9HZJ9
UniRef90 UniRef90_Q9HZJ9

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator PsrA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.41
Kyte-Doolittle Hydrophobicity Value 0.009
Molecular Weight (kDa) 25.8
Isoelectric Point (pI) 9.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2FBQ TRANSCRIPTION 12/09/05 The crystal structure of transcriptional regulator PA3006 Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 285 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002576 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3006
Search term: psrA

Human Homologs

References

PsrA is a positive transcriptional regulator of the type III secretion system in Pseudomonas aeruginosa.
Shen DK, Filopon D, Kuhn L, Polack B, Toussaint B
Infect Immun 2006 Feb;74(2):1121-9
PubMed ID: 16428760
Regulation of rpoS gene expression in Pseudomonas: involvement of a TetR family regulator.
Kojic M, Venturi V
J Bacteriol 2001 Jun;183(12):3712-20
PubMed ID: 11371535