Pseudomonas aeruginosa PAO1, PA3088

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3088
Name
Synonym: yfjB
Replicon chromosome
Genomic location 3466073 - 3466960 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251778.1
GI 15598284
Affymetrix PA3088_at
Entrez 882736
GenBank AAG06476.1
INSDC AAG06476.1
NCBI Locus Tag PA3088
protein_id(GenBank) gb|AAG06476.1|AE004733_3|gnl|PseudoCAP|PA3088
TIGR NTL03PA03088
UniParc UPI00001320BE
UniProtKB Acc Q9HZC0
UniProtKB ID NADK_PSEAE
UniRef100 UniRef100_A6V2Y8
UniRef50 UniRef50_Q4KBJ2
UniRef90 UniRef90_A6V2Y8

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.22
Kyte-Doolittle Hydrophobicity Value 0.017
Molecular Weight (kDa) 32.1
Isoelectric Point (pI) 7.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7QVS STRUCTURAL PROTEIN 01/23/22 Pseudomonas aeruginosa nicotinamide adenine dinucleotide kinase (NADK) structure in complex with NADP Pseudomonas aeruginosa 2.3 X-RAY DIFFRACTION 100.0
7MH7 TRANSFERASE 04/14/21 crystal structure of NAD kinase from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 2.61 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 647 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002504 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3088

Human Homologs

Ensembl 110, assembly GRCh38.p14
NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]
E-value: 1.1e-33
Percent Identity: 28.5
Ensembl 110, assembly GRCh38.p14
NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]
E-value: 1.1e-33
Percent Identity: 28.5
Ensembl 110, assembly GRCh38.p14
NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]
E-value: 1.1e-33
Percent Identity: 28.5

References

No references are associated with this feature.