Pseudomonas aeruginosa PAO1, PA3384 (phnC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3384
Name
phnC
Replicon chromosome
Genomic location 3790150 - 3790986 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252074.1
GI 15598580
Affymetrix PA3384_phnC_at
Entrez 880003
GenBank AAG06772.1
INSDC AAG06772.1
NCBI Locus Tag PA3384
protein_id(GenBank) gb|AAG06772.1|AE004759_19|gnl|PseudoCAP|PA3384
TIGR NTL03PA03384
UniParc UPI00000C59E5
UniProtKB Acc Q9HYL7
UniProtKB ID PHNC2_PSEAE
UniRef100 UniRef100_Q9HYL7
UniRef50 UniRef50_P16677
UniRef90 UniRef90_Q9HYL7

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-binding component of ABC phosphonate transporter
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 8.66
Kyte-Doolittle Hydrophobicity Value -0.106
Molecular Weight (kDa) 30.3
Isoelectric Point (pI) 10.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002244 (828 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3384
Search term: phnC

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:49]
E-value: 2.5e-13
Percent Identity: 30.8
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:49]
E-value: 2.5e-13
Percent Identity: 30.8
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:49]
E-value: 2.5e-13
Percent Identity: 30.8

References

Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B.
Chen CM, Ye QZ, Zhu ZM, Wanner BL, Walsh CT
J Biol Chem 1990 Mar 15;265(8):4461-71
PubMed ID: 2155230