Pseudomonas aeruginosa PAO1, PA3480

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3480
Name
Synonym: dcd
Replicon chromosome
Genomic location 3893432 - 3893998 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252170.1
GI 15598676
Affymetrix PA3480_at
DNASU PaCD00007529
Entrez 878281
GenBank AAG06868.1
INSDC AAG06868.1
NCBI Locus Tag PA3480
protein_id(GenBank) gb|AAG06868.1|AE004769_1|gnl|PseudoCAP|PA3480
TIGR NTL03PA03480
UniParc UPI0000128F91
UniProtKB Acc Q9HYC9
UniProtKB ID DCD_PSEAE
UniRef100 UniRef100_A6V1U5
UniRef50 UniRef50_Q2T083
UniRef90 UniRef90_Q87XN2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable deoxycytidine triphosphate deaminase
Product Name Confidence: Class 3
Synonyms dCTP deaminase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.44
Kyte-Doolittle Hydrophobicity Value -0.252
Molecular Weight (kDa) 21.2
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 368 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002162 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3480

Human Homologs

References

dcd (dCTP deaminase) gene of Escherichia coli: mapping, cloning, sequencing, and identification as a locus of suppressors of lethal dut (dUTPase) mutations.
Wang L, Weiss B
J Bacteriol 1992 Sep;174(17):5647-53
PubMed ID: 1324907