Pseudomonas aeruginosa PAO1, PA3551 (algA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3551
Name
algA
Replicon chromosome
Genomic location 3978031 - 3979476 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252241.1
GI 15598747
Affymetrix PA3551_algA_at
Entrez 879142
GenBank AAG06939.1
INSDC AAG06939.1
NCBI Locus Tag PA3551
protein_id(GenBank) gb|AAG06939.1|AE004776_2|gnl|PseudoCAP|PA3551
TIGR NTL03PA03551
UniParc UPI0000125847
UniProtKB Acc P07874
UniProtKB ID ALGA_PSEAE
UniRef100 UniRef100_P07874
UniRef50 UniRef50_P07874
UniRef90 UniRef90_P07874

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphomannose isomerase / guanosine 5'-diphospho-D-mannose pyrophosphorylase
Product Name Confidence: Class 1
Synonyms Alginate biosynthesis protein AlgA
Evidence for Translation
Charge (pH 7) -14.13
Kyte-Doolittle Hydrophobicity Value -0.210
Molecular Weight (kDa) 53.1
Isoelectric Point (pI) 5.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0091
Category Alginate biosynthesis
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002115 (542 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3551
Search term: algA

References

Purification and characterization of phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase. A bifunctional enzyme in the alginate biosynthetic pathway of Pseudomonas aeruginosa.
Shinabarger D, Berry A, May TB, Rothmel R, Fialho A, Chakrabarty AM
J Biol Chem 1991 Feb 5;266(4):2080-8
PubMed ID: 1846611