Pseudomonas aeruginosa PAO1, PA3557 (arnE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3557
Name
arnE
Synonym: arnE
Synonym: pmrL
Replicon chromosome
Genomic location 3986536 - 3986883 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_252247.1
GI 15598753
Affymetrix PA3557_at
Entrez 879132
GenBank AAG06945.1
INSDC AAG06945.1
NCBI Locus Tag PA3557
protein_id(GenBank) gb|AAG06945.1|AE004776_8|gnl|PseudoCAP|PA3557
TIGR NTL03PA03557
UniParc UPI00000C5A68
UniProtKB Acc Q9HY60
UniProtKB ID ARNE_PSEAE
UniRef100 UniRef100_B7VBM9
UniRef50 UniRef50_Q8X4J8
UniRef90 UniRef90_B7VBM9

Product

Feature Type CDS
Coding Frame 1
Product Name
ArnE
Product Name Confidence: Class 2
Synonyms ArnE
Evidence for Translation
Charge (pH 7) 3.43
Kyte-Doolittle Hydrophobicity Value 0.940
Molecular Weight (kDa) 12.5
Isoelectric Point (pI) 10.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 91 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002109 (407 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3557
Search term: arnE
Search term: ArnE

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance.
Gunn JS, Lim KB, Krueger J, Kim K, Guo L, Hackett M, Miller SI
Mol Microbiol 1998 Mar;27(6):1171-82
PubMed ID: 9570402
An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.
Yan A, Guan Z, Raetz CR
J Biol Chem 2007 Dec 7;282(49):36077-89
PubMed ID: 17928292