Pseudomonas aeruginosa PAO1, PA3607 (potA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3607
Name
potA
Replicon chromosome
Genomic location 4041079 - 4042170 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252297.1
GI 15598803
Affymetrix PA3607_potA_at
DNASU PaCD00007580
Entrez 880429
GenBank AAG06995.1
INSDC AAG06995.1
NCBI Locus Tag PA3607
protein_id(GenBank) gb|AAG06995.1|AE004781_3|gnl|PseudoCAP|PA3607
TIGR NTL03PA03607
UniParc UPI00000C5A8C
UniProtKB Acc Q9HY19
UniProtKB ID POTA2_PSEAE
UniRef100 UniRef100_Q9HY19
UniRef50 UniRef50_Q9HY19
UniRef90 UniRef90_Q9HY19

Product

Feature Type CDS
Coding Frame 1
Product Name
polyamine transport protein PotA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.63
Kyte-Doolittle Hydrophobicity Value -0.100
Molecular Weight (kDa) 40.0
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002067 (366 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3607
Search term: potA

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 10 [Source:HGNC Symbol;Acc:HGNC:41]
E-value: 1.9e-21
Percent Identity: 36.6

References

Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.
Furuchi T, Kashiwagi K, Kobayashi H, Igarashi K
J Biol Chem 1991 Nov 5;266(31):20928-33
PubMed ID: 1939142
Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.
Pistocchi R, Kashiwagi K, Miyamoto S, Nukui E, Sadakata Y, Kobayashi H, Igarashi K
J Biol Chem 1993 Jan 5;268(1):146-52
PubMed ID: 8416922