Pseudomonas aeruginosa PAO1, PA3610 (potD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3610
Name
potD
Replicon chromosome
Genomic location 4043920 - 4044984 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252300.1
GI 15598806
Affymetrix PA3610_potD_at
Entrez 880132
GenBank AAG06998.1
INSDC AAG06998.1
NCBI Locus Tag PA3610
protein_id(GenBank) gb|AAG06998.1|AE004781_6|gnl|PseudoCAP|PA3610
TIGR NTL03PA03610
UniParc UPI00000C5A8F
UniProtKB Acc Q9HY16
UniProtKB ID Q9HY16_PSEAE
UniRef100 UniRef100_Q9HY16
UniRef50 UniRef50_Q82TL3
UniRef90 UniRef90_Q9HY16

Product

Feature Type CDS
Coding Frame 1
Product Name
polyamine transport protein PotD
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -4.09
Kyte-Doolittle Hydrophobicity Value -0.225
Molecular Weight (kDa) 39.3
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 2
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 299 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002064 (300 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3610
Search term: potD

Human Homologs

References

Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.
Furuchi T, Kashiwagi K, Kobayashi H, Igarashi K
J Biol Chem 1991 Nov 5;266(31):20928-33
PubMed ID: 1939142
Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.
Pistocchi R, Kashiwagi K, Miyamoto S, Nukui E, Sadakata Y, Kobayashi H, Igarashi K
J Biol Chem 1993 Jan 5;268(1):146-52
PubMed ID: 8416922
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994