Pseudomonas aeruginosa PAO1, PA3628

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3628
Name
Synonym: yeiG
Replicon chromosome
Genomic location 4062970 - 4063821 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252318.1
GI 15598824
Affymetrix PA3628_at
DNASU PaCD00007590
Entrez 880458
GenBank AAG07016.1
INSDC AAG07016.1
NCBI Locus Tag PA3628
protein_id(GenBank) gb|AAG07016.1|AE004783_1|gnl|PseudoCAP|PA3628
TIGR NTL03PA03628
UniParc UPI00000C5A9A
UniProtKB Acc Q9HY02
UniProtKB ID Q9HY02_PSEAE
UniRef100 UniRef100_W0YY04
UniRef50 UniRef50_A1AXZ2
UniRef90 UniRef90_A6V1G0

Product

Feature Type CDS
Coding Frame 1
Product Name
putative esterase
Product Name Confidence: Class 2
Synonyms probable esterase
Evidence for Translation
Charge (pH 7) -5.82
Kyte-Doolittle Hydrophobicity Value -0.253
Molecular Weight (kDa) 31.2
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 226 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002046 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3628
Search term: putative esterase

Human Homologs

Ensembl 110, assembly GRCh38.p14
esterase D [Source:HGNC Symbol;Acc:HGNC:3465]
E-value: 7.6e-90
Percent Identity: 56.7

References

S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification?
Harms N, Ras J, Reijnders WN, van Spanning RJ, Stouthamer AH
J Bacteriol 1996 Nov;178(21):6296-9
PubMed ID: 8892832