Pseudomonas aeruginosa PAO1, PA3802 (hisS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3802
Name
hisS
Replicon chromosome
Genomic location 4261070 - 4262359 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252491.1
GI 15598997
Affymetrix PA3802_hisS_at
Entrez 878330
GenBank AAG07189.1
INSDC AAG07189.1
NCBI Locus Tag PA3802
protein_id(GenBank) gb|AAG07189.1|AE004798_12|gnl|PseudoCAP|PA3802
TIGR NTL03PA03802
UniParc UPI00000C5B1D
UniProtKB Acc Q9HXJ5
UniProtKB ID SYH_PSEAE
UniRef100 UniRef100_Q02RV6
UniRef50 UniRef50_Q7N705
UniRef90 UniRef90_Q02RV6

Product

Feature Type CDS
Coding Frame 1
Product Name
histidyl-tRNA synthetase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.93
Kyte-Doolittle Hydrophobicity Value -0.178
Molecular Weight (kDa) 47.5
Isoelectric Point (pI) 5.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 667 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001864 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3802
Search term: hisS

Human Homologs

References

Crystal structure of histidyl-tRNA synthetase from Escherichia coli complexed with histidyl-adenylate.
Arnez JG, Harris DC, Mitschler A, Rees B, Francklyn CS, Moras D
EMBO J 1995 Sep 1;14(17):4143-55
PubMed ID: 7556055