Pseudomonas aeruginosa PAO1, PA3818

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3818
Name
Synonym: suhB
Replicon chromosome
Genomic location 4274502 - 4275317 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252507.1
GI 15599013
Affymetrix PA3818_at
DNASU PaCD00007663
Entrez 879908
GenBank AAG07205.1
INSDC AAG07205.1
NCBI Locus Tag PA3818
protein_id(GenBank) gb|AAG07205.1|AE004799_11|gnl|PseudoCAP|PA3818
TIGR NTL03PA03818
UniParc UPI00001361E2
UniProtKB Acc Q9HXI4
UniProtKB ID SUHB_PSEAE
UniRef100 UniRef100_Q9HXI4
UniRef50 UniRef50_P0ADG6
UniRef90 UniRef90_Q9HXI4

Product

Feature Type CDS
Coding Frame 1
Product Name
extragenic suppressor protein SuhB
Product Name Confidence: Class 2
Synonyms SuhB
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.38
Kyte-Doolittle Hydrophobicity Value -0.106
Molecular Weight (kDa) 29.5
Isoelectric Point (pI) 6.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 565 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001848 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3818

Human Homologs

Ensembl 110, assembly GRCh38.p14
inositol monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]
E-value: 1.8e-35
Percent Identity: 37.2

References

A mutation that enhances synthesis of sigma 32 and suppresses temperature-sensitive growth of the rpoH15 mutant of Escherichia coli.
Yano R, Nagai H, Shiba K, Yura T
J Bacteriol 1990 Apr;172(4):2124-30
PubMed ID: 2138605
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994